Search results for "Modelling methods"
showing 4 items of 4 documents
A systematic comparison of kinetic modelling methods generating parametric maps for [11C]-(R)-PK11195
2006
[(11)C]-(R)-PK11195 is presently the most widely used radiotracer for the monitoring of microglia activity in the central nervous system (CNS). Microglia, the resident immune cells of the brain, play a critical role in acute and chronic diseases of the central nervous system and in host defence against neoplasia. The purpose of this investigation was to evaluate the reliability and sensitivity of five kinetic modelling methods for the formation of parametric maps from dynamic [(11)C]-(R)-PK11195 studies. The methods we tested were the simplified reference tissue model (SRTM), basis pursuit, a simple target-to-reference ratio, the Logan plot and a wavelet based Logan plot. For the reliabilit…
Editorial Article for Open Journal of Antennas and Propagation
2013
Antennas help communicate the World. Antennas make possible that millions of people can watch the Champions League. Antennas allow the positioning of billions of vehicles around our planet. And they also allow handling vehicles through our neighbor planets. By propagating waves through antennas you can send huge amounts of data in milliseconds. Besides, you can also tell somebody that you love him or her. Antennas have allowed communicate the people in these places where cables cannot. But antennas are not only used for communication. Antennas can be used for heating food, for detecting people, for guiding vessels, for founding treasures, for monitoring breath, for harvesting energy and so …
Modelling and Simulation of Machining Processes and Operations
2008
This chapter provides the state-of-the-art knowledge engineering and modelling techniques applied in manufacturing/machining and overviews future trends observed at a global scale. Modelling methods for machining processes and operations are classified. The chapter also highlights the multiple tasks of modelling and simulation in modern machining/manufacturing systems. The most popular techniques of numerical simulation including finite difference method and finite element method (FEM) related to mechanical and thermal problems arising in machining processes are described. Practical examples of FE models of various metal cutting operations and their importance in modern manufacturing are pr…
Modeling methods for studying post-translational and transcriptional modifying enzymes.
2012
Biological catalysis is a complex chemical process that involves not only electronic reorganization in the substrate but also the reorganization of the catalyst. This complexity is even larger in the case of post-transcriptional and post-translational modifications which may involve the interaction between two biomacromolecules. However, the development over the past decades of new computational methods and strategies is offering a detailed molecular picture of the catalytic event and a deep understanding of the mechanisms of chemical reactions in biological environments. Here we review the efforts made in the last years to model catalysis in post-transcriptional and post-translational proc…